Biotechnology Essay Example | Topics and Well Written Essays - 2000 words

Biotechnology - Essay ExampleHowever, a more specific approach of the upstream processes will be adopted in this essay. Downstream processes point to the processes that take place after the fermentation process of purification to the packaging of the Biopharmaceuticals. Moreover, the issue of quality concur techniques in a bid to ensure successful harvest-tide analysis will receive tending in this essay.virtuoso of the critical steps in the upstream processing is the choice of an effective burnish and expression system.There atomic number 18 three types of culture systems that may be adopted in the fermentation process. One of them is the hold culture, which is the commonest culture system that used in many industries because of lack of complications. The fact that batch bioreactors are easily available explains why many companies have exhibited preference for it. Batch cultures need to be lactating with all the required nutrients and substrates, and then inoculated with the selected microorganism. Although it is commonly referred to a closed system, there is an evident need to keep up a measure of exerting control on factors such as pH and aeration. After fermentation runs to completion, product removal follows (Boudreau & McMillan, 2007).Although the batch system has been highly preferred, it presents certain challenges, especially because of the surging lack of constancy in the producing formation. In the initial phase when the microorganism is undergoing growth, there is no productivity. Moreover, accumulation of the product also limits but production (Buckel, 2001). In other cases, the presence of a high substrate concentration in the initial phase serves as a form of inhibition. In a bid to address this challenge, the development if ply batch where an inflow is introduced was a benchmark of success. Although the batch culture still has some of the outstanding disadvantages of the batch culture, the fed-batch